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“Providing the highest Quality Glutathione Available”

Molecular structure of reduced glutathione used with all products

The GlutaGenic team would like to congratulation you on your commitment to take your health to the next level. As you explore the website, you are taking the first step towards transforming your level of energy. vitality, and health status. We are excited to share our ideas and effective products with you because they represent a monumental shift in healthcare delivery. 

Imagine a world where 80% of patients are not just chronically managed, where the national healthcare system isn’t ranked 37th in the world, where up to 90% of bankruptcies weren’t due to unpaid medical bills, where 1 out of 2 Americans didn’t die of heart disease, 1 out of 2 didn’t achieve cancer, 1 out of 3 didn’t die of cancer, 1 out of 6 didn’t die of diabetes, and where the healthcare costs of a company’s employees wouldn’t bankrupt one of the largest corporations in the world.

Glutagenic utilizes high potency Glutathione via effective delivery methods such as nebulization, suppository, and endonasal routes. Click the buttons below to explore videos illustrating how Glutathione has made a difference in the health status of various individuals.

In order to attain the physical, psychological, and physiological vibrancy that you desire and deserve, you must weave this information into the fabric of your life. Most of you realize that your physical health is the most important thing that you possess. Utilizing the resources and products at, you too can have the health, energy, and vitality you deserve.

Best wishes,





John Lieurance, D.C., N.D.

& the GlutaGenic Team



Parkinson’s disease, pesticides, and glutathione transferase polymorphisms. | Toxins and Parkinsons | Detox the brain with glutathione for parkinsons

See below article on how low glutathione levels can make on susceptible to injury to the brain which could become Parkinsons from pesticide exposure. Keep in mind that Glutathione is poorly absorbed through the GI tract when taken orally. The reason for the suppository for is that it’s absorbed there and you have a slow release of Glutathione through the colon that peaks for about 5-6 hours. Thats an amazing time frame that your body has to absorb the Glutathione into the brain and into the cells of your body. GlutaGenic also keeps it’s high potency products cold through storage and shipping which ensures the most potent product on the market. Try a month and see the difference. 

The Lancet

Volume 352, Issue 9137, 24 October 1998, Pages 1344–1346



Parkinson’s disease is thought to be secondary to the presence of neurotoxins, and pesticides have been implicated as possible causative agents. Glutathione transferases (GST) metabolise xenobiotics, including pesticides. Therefore, we investigated the role of GST polymorphisms in the pathogenesis of idiopathic Parkinson’s disease.


We genotyped by PCR polymorphisms in four GST classes (GSTM1, GSTT1, GSTP1, and GSTZ1) in 95 Parkinson’s disease patients and 95 controls. We asked all patients for information about pesticide exposure.


The distribution of the GSTP1 genotypes differed significantly between patients and controls who had been exposed to pesticides (controls vs patients: AA 14 [54%] of 26 vs seven [18%] of 39; AB 11 [42%] of 26 vs 22 [56%] of 39; BB 1 [4%] of 26 vs six [15%] of 39; AC 0 vs four [10%] of 39, p=0.009). No association was found with any of the other GST polymorphisms. Pesticide exposure and a positive family history were risk factors for Parkinson’s disease.


GSTP1-1, which is expressed in the blood-brain barrier, may influence response to neurotoxins and explain the susceptibility of some people to the parkinsonism-inducing effects of pesticides.

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Glutathione peroxidase activity in Parkinson’s disease brain | best way to take glutathione |Suppository Glutathione

Keep in mind that Glutathione is poorly absorbed through the GI tract when taken orally. The reason for the suppository for is that it’s absorbed there and you have a slow release of Glutathione through the colon that peaks for about 5-6 hours. Thats an amazing time frame that your body has to absorb the Glutathione into the brain and into the cells of your body. GlutaGenic also keeps it’s high potency products cold through storage and shipping which ensures the most potent product on the market. Try a month and see the difference. 


Glutathione peroxidase is an enzyme of major importance in the detoxification of peroxides in brain. Using the spectrophotometric procedure of Paglia and Valentine [8] and Beutler [2] we measured the activity of this enzyme in autopsied brain from 12 patients dying with idiopathic Parkinson’s disease and 11 neurologically normal adults matched with respect to age and postmortem interval. In the Parkinson’s disease patients glutathione peroxidase activity was slightly but significantly reduced in several brain areas including substantia nigra. Although the magnitude of the glutathione peroxidase deficiency in Parkinson’s disease substantia nigra was small (19% reduction), coupled with the reported marked deficiency of reduced glutathione [9] it may represent one of the contributing factors leading to nigral dopamine neurone loss.

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Alterations in glutathione levels in Parkinson’s disease and other neurodegenerative disorders affecting basal ganglia. | Glutathione Suppositories | Glutathione nebulize

Below is an article that shows how low glutathione levels are present in many degenerative neurological conditions. Keep in mind that Glutathione is poorly absorbed through the GI tract when taken orally. The reason for the suppository for is that it’s absorbed there and you have a slow release of Glutathione through the colon that peaks for about 5-6 hours. Thats an amazing time frame that your body has to absorb the Glutathione into the brain and into the cells of your body. GlutaGenic also keeps it’s high potency products cold through storage and shipping which ensures the most potent product on the market. Try a month and see the difference. 


Reduced glutathione (GSH) and oxidized glutathione (GSSG) levels were measured in various brain areas (substantia nigra, putamen, caudate nucleus, globus pallidus, and cerebral cortex) from patients dying with Parkinson’s disease, progressive supranuclear palsy, multiple-system atrophy, and Huntington’s disease and from control subjects with no neuropathological changes in substantia nigra. GSH levels were reduced in substantia nigra in Parkinson’s disease patients (40% compared to control subjects) and GSSG levels were marginally (29%) but insignificantly elevated; there were no changes in other brain areas. The only significant change in multiple-system atrophy was an increase of GSH (196%) coupled with a reduction of GSSG (60%) in the globus pallidus. The only change in progressive supranuclear palsy was a reduced level of GSH in the caudate nucleus (51%). The only change in Huntington’s disease was a reduction of GSSG in the caudate nucleus (50%). Despite profound nigral cell loss in the substantia nigra in Parkinson’s disease, multiple-system atrophy, and progressive supranuclear palsy, the level of GSH in the substantia nigra was significantly reduced only in Parkinson’s disease. This suggests that the change in GSH in Parkinson’s disease is not solely due to nigral cell death, or entirely explained by drug therapy, for multiple-system atrophy patients were also treated with levodopa. The altered GSH/GSSG ratio in the substantia nigra in Parkinson’s disease is consistent with the concept of oxidative stress as a major component in the pathogenesis of nigral cell death in Parkinson’s disease.

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Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson’s disease | Glutathione suppositories | Glutathione nebulize


Reduced and oxidized glutathione concentrations in post-mortem brain tissue from the substantia nigra of control subjects and patients with neuropathologically confirmed Parkinson’s disease were measured by a coulometric method using high-pressure liquid chromatography and electrochemical detection. Reduced glutathione concentrations were decreased in the substantia nigra of parkinsonian patients compared with controls. Differences in the concentration of oxidized glutathione and in the percentage of oxidized glutathione of the total glutathione were not observed between parkinsonian and control subjects. The finding that oxidized glutathione is not decreased in Parkinson’s disease suggests that the decrease in reduced glutathione is not exclusively the consequence of neuronal loss in the substantia nigra but may indicate a state of oxidative stress.

Keep in mind that Glutathione is poorly absorbed through the GI tract when taken orally. The reason for the suppository for is that it’s absorbed there and you have a slow release of Glutathione through the colon that peaks for about 5-6 hours. Thats an amazing time frame that your body has to absorb the Glutathione into the brain and into the cells of your body. GlutaGenic also keeps it’s high potency products cold through storage and shipping which ensures the most potent product on the market. Try a month and see the difference.

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Extra Secret: What is a Micro Glia and why can this create brain damage?

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Microglia are a type of glial cell that are the resident macrophages of the brain and spinal cord, and thus act as the first and main form of active immune defense in the central nervous system (CNS). Microglia constitute 20% of the total glial cell population within the brain.[1] Microglia (and astrocytes) are distributed in large non-overlapping regions throughout the brain and spinal cord.[2][3] Microglia are constantly scavenging the CNS for plaques,damagedneurons, and infectious agents.[4] The brain and spinal cord are considered “immune privileged” organs in that they are separated from the rest of the body by a series of endothelial cells known as the blood–brain barrier, which prevents most infections from reaching the vulnerable nervous tissue. In the case where infectious agents are directly introduced to the brain or cross the blood–brain barrier, microglial cells must react quickly to decreaseinflammation and destroy the infectious agents before they damage the sensitive neural tissue.

How to preserve your brain with Oxygen and Glutathione. What is the Blood Brain Barrier? from Wellington Chen, M.D. on Vimeo.


Extra Secret: How to Avoid Neuro-Degeneration or Brain Death!

In order to avoid brain degeneration you must avoid inflammation of the brain. Since the brain doesn’t have pain sensation like other area’s of your body inflammation of the brain shows up as brain fog, balance and coordination problems, and poor memory. Digestion is key to maintaining a healthy immune system for 2 key reasons. One when your digestion is poor then your gut is inflamed and when your gut is inflamed you are likely to have a poor barrier which protects the absorption of foods that are partially broken down and metabolized. These foods are a source of immune reaction and can cause autoimmune , arthritis, hypothyroid, fatigue and generally chronic inflammation in the body and brain. The second reason is the lamina propria sub-layer and the submucosa layer of the small intestine have nodules that are part of the lymphatic system. These nodules contain white blood cells that destroy germs. Another common sense reason that poor digestion will effect your immune system is that many nutrients that are key to a healthy immune system will simply not be absorbed like zinc & B vitamins. When your brain becomes inflamed you have to quench this inflammation! Guess what is the main substance that does this in your brain and even to a large part your entire body?……….. Glutathione! If you’ve never heard of Glutathione then it’s likely you will hear much more about it moving forward as it’s your bodies main antioxidant. In the following paragraphs we will look at a few dietary considerations as well as the concept of oxidative stress, the silent killer. Read carefully to keep your brain healthy!

Neurodegeneration & Oxidata Testing. from Wellington Chen, M.D. on Vimeo.

Soy, Glutamate, and MSG

Well hidden in so many processed foods, glutamate in the form of monosodium glutamate (MSG), soy protein extract, protein isolate, hydrolyzed vegetable proteins, natual flavoring or any of the other disguised names for MSG. Its so difficult to avoid as most fast-food chains and restaurants use at least one of these forms of glutamate to enhance the taste of there food.  These substances are toxic to your brain due to an excitatory and inflammatory action they have on the neuron. They call it an excitotoxin were it literally excites the cell to the point of self destruction.

Effects of MSG on Aging and Brain Inflammation.

In 1969, Dr. Olney noticed brain destruction of test animals in the area of the hypothalamus called the arcuate nucleus. The arcuate nucleous releases a substance that is necessary for the pituitary to release growth hormone. The pituitary gland, under normal conditions, secretes growth hormone in cycles. There is usually release that occurs when we fall asleep or take a nap!  This is an excellent reason for us to take a nap during the day (see restorative pose, Chap. 14), also children are benefited greatly due to the large demand of growth hormone. I have seen recent news stories where schools have stopped providing nap time due to striving to increase education. This is a big mistake, in my opinion. In regards to the above study on MSG and its effect of growth hormone release they found animals fed MSG not only produced less growth hormone, they also lacked the normal release cycles seen in all other mammals, including humans.6

Studies using immature mice have shown decreases in LH, FSH and prolactin  which are sex and reproductive hormones, growth hormone, adrenal regulating hormone, and thyroid regulating hormone following exposure to MSG. Deficiencies  in these hormones showed up in the animals as obesity, smaller growth, inability to reproductive, and slow metabolism. 9-13

Confirmation from more studies demonstrating males with atrophy of the testes and low levels of testosterone. Females where seen with low LH, FSH and estradiol-17beta which is the main form of estrogen hormone. In There was a 68% drop after MSG was given. 10

The young girls who begin developing breasts, and beginning menses, earlier than normal may be due to glutamate consumption. Since soy contains phytoestrogens and high glutamate levels consuming soy can be a leading factor for this anomaly.13

Studies found that infant animals given  MSG have high cortisol levels than normal mice, and after stressful events it would take longer for the high levels to come down to normal levels.14

There is an area in the brain called the hippocampus and it is where your memerory centers are located. Its though that high cortisol can cause damage to these neurons through up regulating oxidation in this area. Damage and degeneration of the hippocampus results in the condition known as Alzheimer’s disease. Its though by some that having cortisol levels elevated chronically  from childhood can be quite impactful in ones ability to enjoy memory. The clearence factor is the ability to unwind and I’ve found that treating the high cortisol levels make a big impact on the ability to relax after a tuff day as well as not get so worked up over small events that would otherwise get them excited, elevating their cortisol. Studies have shown that there is a low glutathione saturation in the hippocampus which leads to this damage and inflammation.

Oxidative Stress, Rust

When metal rusts, it’s a sign of the chemical process known as oxidation. Rusting indicates the damage incurred by exposure to oxygen; we say the metal is becoming oxidized. Its when oxygen steals electron from the metal that it distroys the metal changing the physical and chemical properties. Oxidation also takes place when you bite into an apple if left out it will  turn brown as it’s exposed to oxygen in the atmosphere. The process of oxidation causes molecules with uncoupled electrons. These are called free radicals and they are linked to DNA damage which creates cancer cells, aging of organs and skin, arthritis and too many other degenerative diseases to name.

We all need oxidants in our body. However too much oxidant molecules can cause injury to our body.  Oxidative stress is the technical name for this process. This phenomenon was first noted in 1954 by Dr. Denham Harmon, an organic chemist at the University of California, Berkeley. Dr. Harmon theorized that oxidants were the cause of aging, as well as the major cause of most diseases. His theory has continued to hold up and has received substantial verification over the past half century. 

Most of the conditions that we associate with aging, such as wrinkles, heart disease, and Alzheimer’s, are related to excess oxidative stress in the body. As Dr. Harmon stated, “Very few individuals, if any, reach their potential maximum life span; they die instead prematurely of a wide variety of diseases—the vast majority being ‘free radical’ diseases.” Although Dr. Harmon’s research is a half-century old, in the last five years alone, more than five thousand articles on the subject have appeared in research journals. Until recently, tests to measure levels of oxidative stress were expensive and only available to research centers. Today there is, an extremely acurate, over-the-counter urine test available called an oxidata test. Information is available at


Sources of oxidative stress can be both internal and external. The external ones include exposure to any kind of environmental pollution, petrochemicals, or heavy metals. There are also lifestyle-related causes of oxidative stress, such as smoking, drinking alcohol, caffinated beverages like coffee and tea, excessive exercise, prescription drug-and especially overeating. Trying too hard to get a tan can also hurt too much sun (ultraviolet radiation) contributes to oxidative stress.

Internal sources of oxidative stress include infections  (both  acute and/or chronic), blood sugar imbalance lead to increased free radicals,  high levels of adrenaline and  high levels cortisol.

Reduction / Dampness

When your body is subjected to chronic oxidation over a period of time the body can become saturated with electrons. This congests a part of your cell called the mitochondria, its the part of your cell that generates all your energy. When this saturation occurs it’s called reduction. In Chinese medicine they call this dampness. Classically these people will be fatigued usually with a feeling of heaviness. Often the tongue is swollen, observed with tooth marks on the sides of the tongue.  This would not be a good time to take high amounts of anti-oxidants. This represents a good example of why nutrition programs should be closely monitored by a competent clinician with the ability to check these levels for you. Many times this shows up with a low oxidata score with abnormal adrenal states.

Vitamine C with very high bioflavinoids

Recent studies have demonstrated that flavinoids are powerful antioxidants, acting against a whole host of dangerous free radicals. In fact, some of the flavonoids can neutralize special free radicals that cannot be neutralized by antioxidant vitamins. It should be noted that there are other dangerous radicals besides oxygen radicals. Many people are unaware of  a reactive nitrogen species that can be equally, if not more, destructive than oxygen radicals (free radicals). Vitamins are poor at neutralizing these special types of radicals, while flavonoids are very efficient. I regularly test for nitate levels inpateints and bioflavinoids will greatly help normalize these levels. Many times the liver is doing a poor job and neutralizing these compounds usually due to being overburdened with toxicity Its common for these high nitrate levels to cause swelling and congestion of the sinuses. Many of the chronic sniffls, runny noses and post nasal drips are a result of excessive nitrat levels.

Flavonoids can remove (chelate) dangerous metals, such as, copper, aluminum, mercury, arsenic and lead.   Iron and aluminum accumulation is commonly associated with degenerative disorders of the nervous system such as Alzheimer’s and Parkinson’s disease.

Its the flavonoids and carotenoids that allow plants to survive in the glaring sun all day long. Without flavinoids the sun’s harsh rays would quickly destroy the leaves. Flavonoids absorb the harmful radiation from the sun by neutralizing the free radicals they generate. This is similar to how flavinoids work for us!

Recent years has yelded massive research into the medicinal properties of flavonoids. They seem to be finding they not only protect us from antioxidants, they also help in the treatment and prevention of many cancers.

Oxidata Urine testing

This tests for an end product of polyunsaturated fat chain where malondialdehydes form as a result of free radical attack. I include an oxidata urine test with my stadard lab work up on each of my pateints.3-10

Yours In Healhty,


John Lieurance, DC, ND 




1. Dhanakoti S.N., “Response of Urinary Malondialdehyde to Factors that Stimulate Lipid Peroxidation in

Vivo.” Lipids 22(9):643-6, Sept 1987.

2. Draper H.H., “Malondialdehyde Derivatives in Urine.” Basic Life Sci. 49:199-202, 1988.

3. Draper H.H., “Urinary Malondialdehyde as an Indicator of Lipid Peroxidation in the Diet and in the Tis
sues.” Lipids 19(11):836-43, Nov 1984.

4. Hubbard R., lacono R., Westengard J., and Schoonberg T., “Malondialdehyde (MDA) Studies in Palli-
dotomy Treated Parkinson Patients.” To be presented at the Experimental Biology and Medicine Meet
to be held on April 15-18, 2000 at San Diego, CA.

5. Hubbard R., lacono R., Westengard J., and Schoonberg T., “Urine Malondialdehyd (MDA) Measured in
Parkinson Disease, by a Fluorometric and a Visually Read Colormetric Assay.” To be presented at the
Experimental Biology and Medicine Meetings to be held on April 15-18 at San Diego, CA.


6. Lin JY, Pan JT. Single-unit activity of dorsomedial arcuate neurons and diurnal changes of tuberoinfundibular dopaminergic neuron activity in female rats with neonatal monosodium glutamate treatment. Brain Research Bulletin 48(1999): 103-108. Mailer D, Underwood LE, et al. Neonatal treatment with monosodium glutamate:effects of prolonged growth hormone (GH)- releasing hormone deficiency on pulsatile GH secretion and growth in female rats. Endocrinology 128(1991): 1100-1106.

7. / urinary oxidative stress test.

8.  / Nap machine.

9. Nemeroff CB, Lamartiniere CA, Mason GA, et al. Marked reduction in gonadal steroid hormone levels in rats treated neonatally with monosodium L-glutamate: further evidence for disruption of hypothalamic-pituitary-gonadal axis regulation. Neuroendocrinology 33(1981): 265-267. Miskowlak B, Limanowski A, Partyka M. Effect of perinatal administration of monosodium glutamate (MSG) on the reproductive system of the male rat. Endokrynol Pol 44(1993): 497-505.


10. Nemeroff CB, Lamartiniere CA, Mason GA, et al. Marked reduction in gonadal steroid hormone levels in rats treated neonatally with monosodium L-glutamate: further evidence for disruption of hypothalamic-pituitary-gonadal axis regulation. Neuroendocrinology 33(1981): 265-267. Miskowlak B, Limanowski A, Partyka M. Effect of perinatal administration of monosodium glutamate (MSG) on the reproductive system of the male rat.
Endokrynol Pol 44(1993): 497-505.


11. Miskowiak B, Kesa B, Limanowski A, et al. Long-term effect of neonatal monosodium glutamate (MSG) treat
ment on reproductive system of the female rat. Folia Morphol (Wan.) 58(1999): 105-113.


12. Macho L, Jezova D, et al. Postnatal monosodium glutamate treatment results in attenuation of corticosterone metabolic rate in adults rats. Endocrine Regulation 33(1999): 61-67. Miskowiak B, Partyka M. Effect of neonatal treatment with MSG (monosodium glutamate) on thyroid of the adult male rats. Histology and Histopathology 14(1999): 63-67.


13. Hsieh Y-L, Hsu C, Lue S-I, et al. The neonatal neurotoxicity of monosodium L-glutamate on the sexually dimor
phic nucleus of the preoptic area of rats. Neuroscience 19(1997): 342-347.


14. Skuletyova I, Kiss A, Jezova D. Neurotoxic lesions induced by monosodium glutamate result in increased adrenopituitary proopiomelanocortin gene expression and decreased corticosterone clearance in rats. Neuroendocrinology 67(1998): 412-420.


Kato K, Hamada N, et al. Depression of delayed-type hypersensitivity in mice with hypothalamic lesion induced
by monosodium glutamate: involvement of neuroendocrine system in immunomodulation. Immunology 58(1986):

260Vowerk CK, Gorla MS, Dreyer EB. An experimental basis for implicating excitotoxicity in glaucomatous optic
neuropathy. Survey Ophthalmology 43(1999): S142-S150.

261Kowluru RA, Engerman RL, Case GL, Kem TS. Retinal glutamate in diabetes and effect of antioxidants.
Neurochemistry International 38(2001): 385-390.

242 Olney JW. The toxic effects of glutamate and related compounds in the retina and the brain. Retina 2(1982): 341-359.

263 Blaylock RL. Food additive excitotoxins and degenerative brain disorders. Medical Sentinel 4 6(1999): 212-215.

-” Blaylock RL. Phytonutrients and metabolic stimulants as protection against neurodegeneration and excitotoxicity. Journal of the American Nutraceutical Association 2(2000): 30-39.

265Saito K, Markey SP, Heyes MP. Effects of immune activation on quinolinic acid and neuroactive kynurenines in
the mouse. Neuroscience 51(1992): 25-39.

266Beal MF, Bradley T, Koroschetz HW. Do defects in mitochondrial energy metabolism underlie the pathology of
neurodegenerative disease? Trends in Neurosciences 16(1993): 125-131.




Secret 7: Mental Emotional Stress.

Hyper-Sympathetic State

Your nervous system is divided into the sympathetic and the parasympathetic nervous system. Stess is associated with the sympathetic nervous system which holds your fight or flight response. Your parasympathetic nervous system holds your resting and digesting signals. Many of my patients who are stressed out present to my office with a dominance of the sympathetic nervous system.  Some Common Causes of stress include; emotional, mental, chemical/nutritional, electromagnetic, structural/postural.

The Adrenals

Your pair of adrenals are located just on top of your kidneys and they are responsible for the production of cortisol, adrenaline and other catocholamines responsible for reving and charging you up in a stress response. When this system is chronically put on alert it leads to what is called a hypersypathetic state.

Prolonged Increases of Cortisol & Adrenaline can paralize your immune system by decreasing: interleukin, natural killer cell activity, T-lymphocytes,and  secretory IgA. STudies have also shown chronic stress responses linked to Increases blood sugar with a decreases insulin sensitivity (see hyperinsulinemia in chapter 11), Increases bone loss, Increases blood fats (cholesterol, triglycrides), Increases fat accumulation (especially at waist), Increases fluid retention, Increases protein breakdown (thats loss of muscle).

Symptoms of being in a hypersypathetic state include; increased allergies, osteoporotic tendencies,  loss of lean mass, increased infections, blood sugar swings, high cholesterol, obesity, edema, and poor carbohydrate utilization.

Mental and Emotional stress is very common in our society with busy schedules and deadlines to meet. Most americans are working more hours. An interesting fact is that our productivity is staying about thew same is the last couple of years, however our overall unemployment is unchanged. This says that people are working harder to keep up with production. We are the hard working “Japan” of the 1980’s!

The pH Challenge

I include a saliva pH challenge as a part of my basic lab work up,  what we do is introduce a half cup of lemon into the mouth and the pH of the saliva is checked every minute for 5 minutes. I often see a rapid rise in the saliva pH, this is a comom sign that there is a dominance of the sympathetic nervous system.

When your brain becomes stressed from adrenal stress it leads to inflamed. You have to quench this inflammation! Guess what is the main substance that does this in your brain and even to a large part your entire body?……….. Glutathione! If you’ve never heard of Glutathione then it’s likely you will hear much more about it moving forward as it’s your bodies main antioxidant.  We will look at a few dietary considerations as well as the concept of oxidative stress, the silent killer. 

Yours in Health,





John Lieurance, DC, ND

Welcome to the 7 Secrets to Raising Glutathione!

Welcome to Dr. John’s Seven Secrets to Raising Glutathione!

So lets look at an example of how you might apply some of these idea’s into practical solutions. As a physician some of the common problems people have with oxidative stress is poor nutrition. As a society we eat many foods that are void of nutrients. That means protein, carbohydrate, fat, vitamins and minerals. Keep in mind that an orange 50 years ago don’t have the same nutrient value that it has now. 50 years ago the soil wasn’t as over farmed and the mineral content was significantly higher. That means that an orate just doesn’t have the same amount of vitamin C as it used to have. That means you might consider eating more foods that are a denser food source. Examples are things like parsley. the darker and brighter generally the more dense.


The 10 featured here were chosen because of their direct ability to increase  Brain and Body Glutathione levels. These foods (listed here in alphabetical order) are rich in either the Essential Fatty Acids (EFAs), antioxidants or fiber, and as in the case of açaí—all three!In addition, we have included foods that have been proven to lower or help regulate blood sugar levels—an extremely important factor for all of those concerned with decreasing oxidative stress and slowing the aging process and preventing diabetes, obesity, wrinkles and a host of degenerative diseases.

Health Benefits
The 10 foods included here have incredible health benefits due to their ability to increase Glutathione levels, provide vitamins and minerals. Listed below are just some of the health reasons to include these foods in your diet—every day:

  • Prevent or reduce inflammation
  • Protect Brain Tissue and Optimize Brain Function
  • Help regulate metabolism and burn body fat
  • Lower total cholesterol
  • Lower blood pressure
  • Help protect against heart disease
  • Help protect against cancer
  • Help protect organs from toxins
  • Promote digestive health

Here are the 10 super food’s I have chosen.


  • Açaí Fruit
  • The Allium Family
  • Barley
  • Beans and Lentils
  • Buckwheat
  • Green Foods
  • Hot Peppers
  • Nuts and Seeds
  • Sprouts
  • Yogurt and Kefir

Nature’s Energy Fruit

You’ve likely never even heard of acai fruit, but studies have shown that this little berry is one of the most nutritious and powerful foods in the world! Açaí (ah-sigh-ee) is the high-energy berry of a special Amazon palm tree.

Harvested in the rainforests of Brazil, açaí tastes like a vibrant blend of berries and chocolate. Hidden within its royal purple pigment is the magic that makes it nature’s perfect energy fruit. Açaí is packed full of antioxidants, amino acids and essential fatty acids that stimulate your liver to produce Glutathione. Although açaí may not be available in your local supermarket, you can find it in several health food and gourmet stores (often in juice form).

Açaí pulp contains:

  • A remarkable concentration of antioxidants that help combat premature aging, with 10 times the ability to rise Glutathione levels than red grapes and 10 to 30 times the anthocyanins of red wine.
  • A synergy of monounsaturated (healthy) fats, dietary fiber and phytosterols to help promote cardiovascular and digestive health.
  • An almost perfect essential amino acid complex in conjunction with valuable trace minerals, vital to proper muscle contraction and regeneration.

The fatty acid content in açaí resembles that of olive oil, and is rich in monounsaturated oleic acid. Oleic acid is important for a number of reasons. It helps omega-3 fish oils penetrate the cell membrane; together they help make cell membranes more supple. By keeping the cell membrane supple, all hormones, neurotransmitter and insulin receptors function more efficiently. This is particularly important because high insulin levels create an inflammatory state, and we know, inflammation causes aging. Inflammation also depletes our Glutathione as Glutathione is a primary buffer against inflammation and aging.

Allium Family:

Onions, Garlic, Chives, Leeks, Shallots and Scallions

If açaí is the most exotic food on this list, the allium family of foods is perhaps the most humble. Garlic, onions, leeks and chives contain flavonoids that stimulate the production of Glutathione.  Glutathione enhances elimination of toxins and carcinogens, putting the allium family of vegetables at the top of the list for foods that can help prevent cancer. Here are just a few benefits from members of this family.



  • Lowers total cholesterol (but raises HDL—”good”—cholesterol)
  • Lessens the risk of atherosclerosis (hardening of the arteries)
  • Lowers blood pressure
  • Reduces the risk of blood clots (cause of the majority of strokes and heart attacks)
  • Destroys infection-causing viruses and bacteria
  • Reduces the risk of certain cancers, in particular, stomach cancers
  • Produces more “natural killer” cells in the blood to fight tumors and infections
  • Helps fight against neurological diseases such as Alzheimer’s
  • Enhances detoxification by reducing toxins

For optimum effect, eat garlic raw. Cooking can destroy some of the allicin compound, which is the active constituent. It will keep vampires away also.


This ancient grain is sadly overlooked by today’s culinary trendsetters, yet it is one of the grains with the greatest health benefits, delightful flavor and versatility. Barley can be used as a delicious breakfast cereal, in soups and stews and as a rice substitute for dishes such as risotto.

Not only is barley a low-glycemic grain, it is high in both soluble and insoluble fiber. Soluble fiber helps the body metabolize fats, cholesterol and carbohydrates, and lowers blood cholesterol levels. Insoluble fiber—commonly called “roughage”—promotes a healthy digestive tract and reduces the risk of cancers affecting it (e.g., colon cancer).

Dietary fiber is critical to health—yet few people in our modern society even come close to the recommended daily intake. Many experts believe that good health begins in the colon, and without sufficient dietary fiber in the diet, we run the risk of a host of diseases, ranging from hemorrhoids to colon cancer.

The fiber found in barley provides food for the beneficial bacteria in the large intestine. This is important as the “good” bacteria can crowd out the disease-causing bacteria in the intestinal tract, resulting in greater health and disease resistance.

Barley is sold in many forms, all of which are nutritious. But hulled barley, in which the outer hull (the bran) is left intact, is richer in fiber and contains more fiber and nutrients than other forms, such as pearl barley or Scotch barley.

Eating hulled barley on a regular basis:

  • Lowers blood cholesterol levels
  • Increases Glutathione
  • Protects against cancer because its high fiber content helps speed food through the digestive tract, and because its a good source of selenium, shown to significantly reduce the risk of colon cancer
  • Is a good source of niacin, the B vitamin that is cardio-protective
  • Slows starch digestion, which may help keep blood sugar levels stable
  • Provides high concentrations of tocotrienols, the “super” form of vitamin E
  • Provides lignans, phytochemicals that function as antioxidants. Women who consume lignans (also present in high levels in flaxseed) are less likely to develop breast cancer.

Beans and Lentils

Beans are low in fat (except for soybeans), calories and sodium but high in complex carbohydrates and dietary fiber, and they offer modest amounts of essential fatty acids—mostly omega-6s (only soybeans have significant amounts of omega-3 fatty acids). They are also an excellent source of protein, needing only to be combined with grains such as barley or oats to provide all the amino acids necessary to make a complete protein for vegetarians who do not have other sources of protein for their meals.

Beans are extremely beneficial in an anti-diabetes diet because they rank low on the glycemic scale, which means that they do not cause the inflammatory, hunger-inducing spike in blood sugar levels associated with refined grains and baked goods. Beans offer ample fiber (one cup of cooked beans can provide as much as 15 grams of dietary fiber, more than half the recommended “daily value” of 25 grams and are released into the bloodstream slowly, providing energy and satiation for a sustained period. However, I recommend no more than 1/4 to 1/2 cup cooked beans per meal.

Dried beans and lentils are a staple of many cuisines worldwide. For thousands of years, beans and lentils have been and continue to be one of the most nutritious foods available. In addition, beans and lentils are extremely versatile. They can be combined with fragrant herbs and vegetables and made into delicious soups. They can be used in salads or puréed and served as a dip or spread. Chickpeas and lentils can also be ground into a high-protein, low-glycemic flour.

Green Foods

When we talk about “green foods,” we’re referring to a group of foods that includes young cereal grasses like barley grass and wheatgrass, as well a blue-green algae known as BGA. Nutritionally, they are close cousins to dark green leafy vegetables, but offer far greater levels of “nutrient density.” In other words, an ounce of these concentrated green foods contains much more of the beneficial phytonutrients found in an ounce of green vegetables.

The results of many experimental studies show that green foods have marked beneficial effects on cholesterol, blood pressure, immune response and cancer prevention. These effects are attributed in part to their high concentrations of chlorophyll.

Chlorophyll, the phytochemical that gives leaves, plants and algae their green hues, is the plant equivalent of the oxygen-carrying red pigment hemoglobin in red blood cells. Dietary chlorophyll inhibits disease bacteria and exerts therapeutic effects on bad breath and internal odors.

Wheat and Barley Grasses
Young cereal grasses—especially wheat and barley grass—are distinguished by their brilliant emerald green hues. Before World War II, drug stores throughout the country, but especially in the grain-belt states of the Midwest, sold tablets of dried wheat or barley grass as a kind of primitive vitamin supplement. Today, young wheat and barley grasses are dried and powdered to make dietary supplements, or picked fresh to process in juicing machines.

At the early grass stage of their growth, wheat and barley are closer to vegetables than grains in composition. This is important to note because while I strongly discourage eating wheat and wheat products, I believe wheatgrass is an excellent addition to your diet. Sprouting as mentioned in this article is also ok.

The nutrient profiles of green cereal plants change quickly as they grow. As the plant grows, the chlorophyll, protein and vitamin content of cereal grasses declines sharply and the level of cellulose (indigestible fiber) increases. Over a period of several months, the green leafy cereal grasses become amber waves of grain bearing the kernels we harvest to make into flour—an unhealthy, pro-inflammatory food.

There is very little nutritional difference between wheat grass and barley grass, although it is important to note that barley grass acts as a free radical scavenger that also reduces inflammation and pain, and wheat grass contains P4D1, a “gluco-protein” that acts like an antioxidant, reducing inflammation. It is also thought to be able to help the body attack cancer cells.

You can get cereal grasses in powder or tablet form. Dried cereal grasses are certainly easier to handle than fresh, which must be juiced. However, fresh grass juice contains healthful enzymes not found in dried grass powder and is likely to be higher in just about every phytonutrient found in cereal grass. Many juice bars and health-oriented markets offer these juices on their menus.


The term “peppers” encompasses a diverse group of plants, ranging from the popular sweet green or red bell pepper to the fiery hot habañero or the even more lethal Scotch bonnet. Peppers—whether sweet bell or hot chili—are members of the plant genus “capsicum” (cap-sih-kum), a term that comes from the Greek word kapto, which means “to bite.”

All peppers contain compounds called capsaicinoids. This is especially true of chili peppers, which derive their spicy heat—as well as extraordinary anti-inflammatory, analgesic, anti-cancer, heart-healthy effects—from very high levels of capsaicinoids, the most common form of which is capsaicin.

In addition to capsaicin, chilies are high in antioxidant carotenes and flavonoids, and contain about twice the amount of vitamin C found in citrus fruits. These compounds will increase Glutathione levels.

Almost any dish—from homemade soups, stews and chili to stir-fries, salads and salsas—can benefit from small amounts of hot peppers.



Sprouts are a highly nutritious food. Grown locally year-round, sprouts are a good source of protein and vitamin C. A sprout is produced when a seed starts growing into a vegetable. Sprouts can grow from the seeds of vegetables, grains, legumes, buckwheat and beans. Sprouts vary in texture and taste. Some are spicy (radish and onion sprouts), some are hardy and often used in Asian cuisines (mung bean), while others are more delicate (alfalfa) and add texture and moistness to salads and sandwiches.

Why Sprouts?

Wheat sprout enzymes are another source of bioactive plant flavonoids, and their potential benefits range from improving symptoms of fibromyalgia and joint pain to increasing energy and relieving symptoms of chronic fatigue syndrome. These benefits are likely related to the presence of several potent natural antioxidant enzymes, including superoxide dismutase (SOD), glutathione peroxidase, and catalase. Wheat sprouts represent one rich source of these SOD-boosting building blocks, and have been shown to significantly increase internal antioxidant levels.
All nutrients necessary for life are contained in seeds—a food category that includes grain kernels, beans, legumes and nuts. Because sprouts are so fresh and do not sit for days or weeks in warehouses, we know that we are getting optimum nutrition.

Great Ways to Serve Sprouts

  • Add to tossed salads
  • Use in coleslaw (cabbage, clover, radish)
  • Try in wraps and roll-ups (alfalfa, sunflower, radish)
  • Stir-fry with other vegetables (alfalfa, clover, radish, mung bean, lentil)
  • Blend with vegetable juices (cabbage, mung bean, lentil)
  • Mix with soft cheeses, tofu, yogurt of kefir for a dip (mung bean, radish)
  • Stir into soups or stews when serving (mung bean, lentil)
  • Eat them fresh and uncooked in a sprout salad (salad mixes)
  • Top omelet or scrambled eggs (alfalfa, clover, radish)
  • Combine in oat, barley or buckwheat dishes (fenugreek, lentil, mung bean)
  • Add to sushi (radish, sunflower)
  • Sauté with onions (mung bean, clover, radish)
  • Puree with dried peas or beans (mung bean, lentil)
  • Add to baked beans (lentil)

“Probiotic” Partners in Health
The origin of fermented foods and cultured milk products goes so far back that it is rumored to predate recorded history. This is perfectly in keeping with my philosophy that the most ancient foods have survived for a reason—they continue to be instrumental to the survival of our species. Fermented and cultured foods may well represent our first experience with what researchers now call “functional” foods—foods that actively promote optimal health.

The fermented foods scientists consider “probiotic” are primarily yogurt and kefir.

Nuts and Seeds

If you want to dramatically decrease your risk of cancer, heart disease and diabetes, control your weight with no hunger pangs, improve Glutathione Levels, and reduce the visible signs of aging like wrinkles and sagging skin, I recommend that you “go nuts.”  Brazil nuts are the best nut to eat to raise Glutathione levels due to high levels of cysteine.

Here’s how to go nuts with some meals:

  • When thoughts turn to food between meals, enjoy a handful of raw, unsalted nuts. They’re extremely filling and satisfying—and healthful.
  • Add some nuts to regular meals—a tablespoon of chopped almonds on your oatmeal or a tablespoon of walnuts in your lunchtime salad. Nuts are so versatile they can take the place of flour and breadcrumbs—with a lot more flavor and health benefits. Just remember, as with all things, to use moderation.

Some more of my favorite super foods are Gogi berries, golden berries, mangosteen, and cocao. Begin to search around for super foods as it’s a bit of a buzz word these days and you’ll find many fun items to explore. Try and avoid nutrient void foods like white bread, processed meats and cheeses and sugar/fructose filled drinks.

Try adding just one superfood and keep nutrient void foods to a minimum for the next 7 days as a personal challenge from me.

Until next week, Believe in your bodies ability to heal, I do.








John Lieurance, DC, ND